Puerariae radix prevents bone loss in ovariectomized mice
โ Scribed by Xinxiang Wang; Jian Wu; Hiroshige Chiba; Keizo Umegaki; Kazuhiko Yamada; Yoshiko Ishimi
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 222 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0914-8779
No coin nor oath required. For personal study only.
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## Abstract Osteoporosis is a disease characterized by low bone mass, increased bone fragility, and a greater risk for bone fracture. Currently, pharmacological intervention can generally aid in the prevention and treatment of osteoporosis, but these therapies are often accompanied by undesirable s
This study was conducted to investigate whether hydroxyapatite (HAP) is appropriate as a percutaneous drug carrier for estradiol (E2) for the suppression of bone loss. Tenweek-old female Sprague-Dawley rats were subjected either to bilateral ovariectomy (OVX) or to sham surgery (control). Ovariectom