Pubertal ovarian hormone exposure reduces the number of myelinated axons in the splenium of the rat corpus callosum
โ Scribed by M.A. Yates; J.M. Juraska
- Book ID
- 116459220
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 389 KB
- Volume
- 209
- Category
- Article
- ISSN
- 0014-4886
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The splenium (posterior of the corpus callosum is sexually dimorphic in the 1 โ5) adult rat brain. In the present study we examined the role of developmental hormones and cryoanesthesia (which is normally used during the performance of neonatal hormone manipulations) on the gross size of the spleniu
The effects of prenatal exposure to ethanol on the number of callosal axons were examined. Pregnant Macaca nemestrina were treated with ethanol (1.8 g/kg b.wt.) 1 day per week during the first 6 weeks (Et6) or full 24 weeks (Et24) of gestation. Control macaques were intubated with an isocaloric amou