𝔖 Bobbio Scriptorium
✦   LIBER   ✦

PTK787/ZK 222584, a small molecule tyrosine kinase receptor inhibitor of vascular endothelial growth factor (VEGF), has modest activity in myelofibrosis with myeloid metaplasia

✍ Scribed by Francis J. Giles; Alan F. List; Michael Carroll; Jorge E. Cortes; Joyce Valickas; Bee-Lian Chen; Eric Masson; Christian Jacques; Dirk Laurent; Maher Albitar; Eric J. Feldman; Gail J. Roboz


Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
151 KB
Volume
31
Category
Article
ISSN
0145-2126

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


PTK787/ZK222584, a tyrosine kinase inhib
✍ Markus Rudin; Paul M. J. McSheehy; Peter R. Allegrini; Martin Rausch; Diana Baum 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 793 KB

## Abstract Assessment of tumour vascularity may characterize malignancy as well as predict responsiveness to anti‐angiogenic therapy. Non‐invasive measurement of tumour perfusion and blood vessel permeability assessed as the transfer constant, __K__^trans^, can be provided by dynamic contrast‐enha

Phase II study of SU5416—a small-molecul
✍ Francis J. Giles; Maureen A. Cooper; Lewis Silverman; Judith E. Karp; Jeffrey E. 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 104 KB

## Abstract ## BACKGROUND Increased bone marrow angiogenesis and vascular endothelial growth factor (VEGF) levels are of adverse prognostic significance in patients with myeloproliferative disorders (MPD), including agnogenic myeloid metaplasia (AMM), chronic myeloid leukemia in blastic phase (CML