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PTHrP promotes homotypic aggregation of breast cancer cells in three-dimensional cultures

✍ Scribed by Angela Dittmer; Dario Schunke; Jürgen Dittmer

Book ID
116334557
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
680 KB
Volume
260
Category
Article
ISSN
0304-3835

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## Abstract Breast cancer cell colonization of osteoblast monolayers grown in standard tissue culture (2D) is compared to colonization of a multi‐cell‐layer osteoblastic tissue (3D) grown in a specialized bioreactor. Colonization of 3D tissue recapitulates events observed in clinical samples includ