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PTHrP contributes to the anti-proliferative and integrin α6β4-regulating effects of 1,25-dihydroxyvitamin D3

✍ Scribed by Xiaoli Shen; Ramanjaneya V.R. Mula; Jing Li; Nancy L. Weigel; Miriam Falzon


Book ID
116892088
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
655 KB
Volume
72
Category
Article
ISSN
0039-128X

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The hormone I ,25-dihydroxyvitamin D3 (VD) has a potential use as an anti-tumor agent, but its clinical applications are restricted by its strong calcemic activity. This has led to the development of VD analogues with selectively increased growthinhibitory activity. One of the most potent analogues