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PTH-1R responses to PTHrP and regulation by vitamin D in keratinocytes and adjacent fibroblasts

✍ Scribed by Amina Errazahi; Michèle Lieberherr; Zhor Bouizar; Marthe Rizk-Rabin


Book ID
116697304
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
178 KB
Volume
89-90
Category
Article
ISSN
0960-0760

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PTH and PTHrP have been shown to inhibit maturation of growth plate chondrocytes and the expression of type X collagen. In order to examine the regulatory mechanisms involved, fetal bovine growth plate chondrocytes were incubated for 24-48 h under serum-free conditions with PTH and PTHrP and various