𝔖 Bobbio Scriptorium
✦   LIBER   ✦

PTEN sensitizes prostate cancer cells to death receptor-mediated and drug-induced apoptosis through a FADD-dependent pathway

✍ Scribed by Yuan, Xiu-Juan; Whang, Young E


Book ID
110066277
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
297 KB
Volume
21
Category
Article
ISSN
0950-9232

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## Abstract Resistance to tumor necrosis factor (TNFα)‐induced apoptosis in various cancer cells has been attributed to the activation of the transcription factor NF‐κB. Ebselen (2‐phenyl‐1,2‐benzisoselenazol‐3[2H]one)—a selenoorganic compound is known to prevent TNFα‐mediated NF‐κB activity. As gl