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PTEN augments staurosporine-induced apoptosis in PTEN-null Ishikawa cells by downregulating PI3K/Akt signaling pathway

✍ Scribed by Wan, X; Yokoyama, Y; Shinohara, A; Takahashi, Y; Tamaya, T


Book ID
110016331
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
237 KB
Volume
9
Category
Article
ISSN
1350-9047

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## Abstract We observed that treatment of prostate cancer cells for 24 h with magnolol, a phenolic component extracted from the root and stem bark of the oriental herb __Magnolia officinalis__, induced apoptotic cell death in a dose‐ and time‐dependent manner. A sustained inhibition of the major su