Silencing of the PTEN tumor-suppressor g
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Tony Frisk; Theodoris Foukakis; Trisha Dwight; Jonas Lundberg; Anders HΓΆΓΆg; GΓΆra
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Article
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2002
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John Wiley and Sons
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English
β 189 KB
π 2 views
## Abstract Germline mutations in the tumorβsuppressor gene __PTEN__ (__MMAC1, TEP1__) are found in Cowden syndrome, which predisposes to hamartomas, breast cancer, trichilemmomas, and thyroid tumors of follicular epithelium. __PTEN__ has also been found to be somatically deleted, mutated, and/or s