Psychiatric Symptoms in Huntington’s Disease before Diagnosis: The Predict-HD Study
✍ Scribed by Kevin Duff; Jane S. Paulsen; Leigh J. Beglinger; Douglas R. Langbehn; Julie C. Stout
- Book ID
- 119197503
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 100 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0006-3223
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## Abstract The PREDICT‐HD study seeks to identify clinical and biological markers of Huntington's disease in premanifest individuals who have undergone predictive genetic testing. We compared baseline motor data between gene‐expansion carriers (cases) and nongene‐expansion carriers (controls) usin
Huntington's disease (HD) is an autosomal dominant disease characterized by motor disturbance, cognitive loss and psychiatric manifestations, starting between the fourth and the fifth decade, followed by death within 10-20 years of onset of the disease. The disease-causing mutation is an expansion o