<span>The edition details methods to study intrinsically disordered proteins (IDPs) including recent topics such as extremely high-affinity disordered complexes, kinetics that evade established concepts, liquid-liquid phase separation, and novel disorder-driven allosteric mechanisms. Written in the
Psychiatric Disorders: Methods and Protocols (Methods in Molecular Biology, 829)
β Scribed by Firas H. Kobeissy (editor)
- Publisher
- Humana
- Year
- 2012
- Tongue
- English
- Leaves
- 609
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Synopsis
New high throughput techniques in neuroscience and psychiatry have enhanced the development of experimental, customizable animal models that are predictive of human neuropsychiatric pathology and give vital insights on the mechanisms and pathways involved. In Psychiatric Disorders: Methods and Protocols, key experts have written integrated chapters on neuropsychiatric research sharing their insightful expertise and opinions focusing on both the animal models as well as the cutting edge techniques applied. Beginning with an overview of the animal research in psychiatric illness and substance abuse, this comprehensive volume continues with the modeling of neuropsychiatric illness, drug abuse paradigms and techniques, biomarker identification, autoimmune inflammatory response, and neuroendocrine alteration in the areas of psychiatry, as well as state-of-the-art βOmics approachesβ and neurosystems biology/data mining techniques to compute and analyze genomic and proteomics alteration occurring within neuropsychiatric models.Β As a part of the highly successful Methods in Molecular Biologyβ’ series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Β
Thorough and easily applicable, Psychiatric Disorders: Methods and Protocols offers the detailed and clearly illustrated tools necessary for neuroscientists and psychiatrists to handle many unanswered scientific questions with a more creative and insightful approach.
β¦ Table of Contents
Psychiatric Disorders
Dedication
Foreword
Preface
Acknowledgments
Contents
Contributors
Part I: Overview of the Animal Research in Psychiatric Illness and Substance Abuse
Part II: Methods in Animal Models of Psychiatric Illness
Part III: Methods in Animal Models of Substance Abuse
Part IV: Methods in Animal Models of Eating Disorders
Part V: Biomarkers, Neuroendocrine and Inflammatory Profiles Relevant to Neuropsychiatric Disorders
INDEX
π SIMILAR VOLUMES
Since its discovery, the mammalian target of rapamycin (mTOR) has been shown to regulate many critical molecular processes in eukaryotes such as metabolism, growth, survival, aging, synaptic plasticity, memory, and immunity. In mTOR: Methods and Protocols expert researchers in the field detail many
This book investigates the various processes that are affected by the age of an organism. Several new tools for the analysis of biological aging have been introduced recently, and this volume provides methods and protocols for these new techniques in addition to its coverage of established procedure
<span>This detailed volume explores molecularly imprinted polymers (MIPs), which have attracted great interest both in fundamental research and for practical applications due to their selective molecular recognition capabilities, extraordinary stability, and ease of preparation. Beginning with key l
The germline is unique in mammals as it is the only cell lineage that undergoes mitosis, meiosis, and differentiation, making these cells amenable to in-depth genomic and mechanistic studies. In Germline Development: Methods and Protocols, expert researchers provide a wide-ranging collection of tech
<p><span>The germline is unique in mammals as it is the only cell lineage that undergoes mitosis, meiosis, and differentiation, making these cells amenable to in-depth genomic and mechanistic studies. In </span><span>Germline Development: Methods and Protocols</span><span>, expert researchers provid