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pSTAT1, pSTAT3, and T-bet as markers of disease activity in chronic inflammatory demyelinating polyradiculoneuropathy

✍ Scribed by Francesca Madia; Giovanni Frisullo; Viviana Nociti; Amelia Conte; Marco Luigetti; Alessandra Del Grande; Agata Katia Patanella; Raffaele Iorio; Pietro Attilio Tonali; Anna Paola Batocchi; Mario Sabatelli

Book ID: 109116293
Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 662 KB
Volume: 14
Category: Article
ISSN: 1085-9489
DOI: 10.1111/j.1529-8027.2009.00220.x

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## Abstract Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system, and it is considered to be a T helper 1 (Th1) cell‐mediated autoimmune disease. T‐bet has been identified as a key transcription factor for the development of Th1 cells and the inducti