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Psoriasis: response to high-dose intravenous immunoglobulin in three patients

✍ Scribed by V. Gurmin; R. Mediwake; M. Fernando; S. Whittaker; M.H.A. Rustin; H.L.C. Beynon

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 59 KB
Volume: 147
Category: Article
ISSN: 0007-0963
DOI: 10.1046/j.1365-2133.2002.04753.x

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✦ Synopsis

Treatment of recalcitrant psoriasis and psoriatic arthritis can be challenging, with treatment options limited by drug intolerance or poor efficacy. High-dose intravenous immunoglobulin (hdIVIg) has been used successfully in Kawasaki's disease and idiopathic thrombocytopenic purpura, where it has become the standard treatment. The literature also suggests its positive effect in the treatment of dermatological conditions, such as autoimmune chronic urticaria, atopic dermatitis, scleromyxoedema, dermatomyositis and autoimmune bullous disorders. We report three patients with treatment-resistant psoriasis and psoriatic arthritis who improved with hdIVIg.

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