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Psorias, Methotrexate and Tuberculosis

✍ Scribed by I. S. Hodgson-Jones


Book ID
108652620
Publisher
John Wiley and Sons
Year
1971
Tongue
English
Weight
85 KB
Volume
85
Category
Article
ISSN
0007-0963

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πŸ“œ SIMILAR VOLUMES


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✍ Heiko Iven; Helmut Brasch; JΓΆrg Engster πŸ“‚ Article πŸ“… 1985 πŸ› Springer 🌐 English βš– 551 KB

In rabbits the IV kinetics of MTX (1.33, 4 and 12 mg/kg) could be described by a linear three-compartment model with a terminal half-life between 2.4 and 3.6 h. During 8 h 50% of the dose was excreted into urine in unchanged form and 15% as the metabolite 7-OH-MTX. These fractions remained constant