PSORALENS, UVA (PUVA) AND PHOTOCARCINOGENESIS
β Scribed by David A. Grekin; John H. Epstein
- Book ID
- 114893634
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 329 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0031-8655
No coin nor oath required. For personal study only.
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The influence of methotrexate and of betamethasone on a following phototoxic reaction to 8-methoxypsoralen and long-wave ultraviolet light (PUVA) was studied in the mouse. High PUVA doses were not influenced by the two drugs tested. Both methotrexate and betamethasone tended to diminish the PUVA res
Treatment of human lymphocytes in vitro with trimethylpsoralen or 8-methoxypsoralen and UVA irradiation (PUVA) induced chromosome damage, mainly constrictions and gaps, but also breaks and exchanges, and increased the frequency of sister chromatid exchange (SCE). The localization of the chromosome a