โ Scribed by Harold E. Miller; Henri B. Kagan; Walter Renold; Tom J. Mabry
No coin nor oath required. For personal study only.
We wish to report the structure of psilostachyin, I, a new sesquiterpene lactone from Ambrosia psilostachyia, and its synthesis from coronopilin, VIII. Hers and Hogenauer (1) previously established the structure of coronopilin, a sesquiterpene lactone isolated from 5. psilostachyia obtained in Kansas. More recently, Gelssman and Turley (2) described the acid-catalyzed dehydration-rearrangement of coronopilin to coronopilic acid, IX, which argued for the stereochemical features of VIII, previously proposed by Hers and co-workers(3) on the basis of the tentative absolute configuration of parthenin which had been directly correlated to coronopilin. * N.I.H. Pre-doctoral Trainee.
๐ SIMILAR VOLUMES
A new sesquiterpene lactone called aquatolide was isolated from the hexane extract of Asteriscus aquaticus. Its constitution and stereochemistry were deduced from spectroscopic data, mainly homonuclear and heteronuclear two-dimensional NMR correlations. From the neutral part of a methanol deffated