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Pseudomonas aeruginosaelastase induces IL-8 production in the lung cells via the epidermal growth factor/extracellular signal-regulated proteins/NFκB pathway

✍ Scribed by Ali Azghani


Book ID
126388711
Publisher
Springer (Biomed Central Ltd.)
Year
2008
Tongue
English
Weight
930 KB
Volume
12
Category
Article
ISSN
1466-609X

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## Abstract Blood vessel injury results in limited oxygen tension and diffusion leading to hypoxia, increased anaerobic metabolism, and elevated production of acidic metabolites that cannot be easily removed due to the reduced blood flow. Therefore, an acidic extracellular pH occurs in the local mi