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PS2-01 Schistosoma Mansoni Antigens Down-Modulate the Th2-allergic response in vitro

✍ Scribed by Luciana S. Cardoso; Sérgio C. Oliveira; Alfredo M. Góes; Ricardo R. Oliveira; Edgar M. Carvalho; Marshall J. Glesby; Maria Ilma Araujo

Book ID: 116399687
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 138 KB
Volume: 52
Category: Article
ISSN: 1043-4666
DOI: 10.1016/j.cyto.2010.07.206

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## Abstract We examined the role of TLR3 in Th2‐driven pulmonary granulomatous disease, using wildtype (TLR3^+/+^) and TLR3 gene‐deficient (TLR3^−/−^) mice in a well‐established model of __Schistosoma mansoni__ egg‐induced pulmonary granuloma. The intravenous bolus injection of __S. mansoni__ eggs