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PS1-016. Role of TGF-β-Smad2/3 signaling in helper T cell function and differentiation

✍ Scribed by Akihiko Yoshimura; Kenji Ichiyama; Ikko Kashiwagi

Book ID
116400140
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
32 KB
Volume
56
Category
Article
ISSN
1043-4666

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## Abstract Transforming growth factor‐beta (TGF‐β) is an important growth inhibitor of epithelial cells, and insensitivity to this cytokine results in uncontrolled cell proliferation and can contribute to tumorigenesis. Smad2 and Smad3 are direct mediators of TGF‐β signaling, however little is kno