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PS-IIDQ: A Supported Coupling Reagent for Efficient and General Amide Bond Formation.

✍ Scribed by Eric Valeur; Mark Bradley

Publisher
John Wiley and Sons
Year
2007
Weight
27 KB
Volume
38
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

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DEPBT as an efficient coupling reagent f
DEPBT as an efficient coupling reagent for amide bond formation with remarkable resistance to racemization
✍ Yun-hua Ye; Haitao Li; Xiaohui Jiang πŸ“‚ Article πŸ“… 2005 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 172 KB πŸ‘ 2 views

## Abstract 3‐(Diethoxyphosphoryloxy)‐1, 2, 3‐benzotriazin‐4(3H)‐one (DEPBT) is an effective coupling reagent for synthesis of linear and cyclic peptides by both solution and solid‐phase peptide synthesis. DEPBT mediates amide bond formation with remarkable resistance to racemization. When DEPBT is