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Préparation d’orthoesters originaux par addition d’acides carboxyliques sur des acétals cycliques de cétènes

✍ Scribed by Pierre Babin; Stéphanie Desrousseaux; Sophie Tabuteau; Nadège Vincent; Bernard Bennetau


Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
112 KB
Volume
6
Category
Article
ISSN
1631-0748

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A previously described method consisting in reacting LDA with u-bromoketones has been ertended t o u-bromoesters. DeshaZogemtion ( a f t e r hydrolysis) and f o n a t i o n of ketene alkyZtrimethyZsiZyZ acetaZ8 ( a f t e r SiMejCZ addition) occur and show the genemZity of the method.