✦ LIBER ✦
Präparative Enantiomerentrennung einer Chroman-2-carbonsäure durch Chromatographie von Glucose-Derivaten
✍ Scribed by Netscher, Thomas ;Gautschi, Iwan
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 470 KB
- Volume
- 1992
- Category
- Article
- ISSN
- 0947-3440
No coin nor oath required. For personal study only.
✦ Synopsis
Preparative Separation of the Enantiomers of a Chroman‐2‐carboxylic Acid via Chromatography of Glucose Derivatives
Starting from the commercially available racemic carboxylic acid 2a, b (S)‐Trolox methyl ether (1a), useful as a chiral reagent for capillary gas chromatography and supercritical fluid chromatography, was obtained in enantiomerically pure form (e.e. >99.9%) by the separation of esters derived from diacetone D‐glucose and subsequent saponification.