Prunella vulgarisextract and rosmarinic acid prevent UVB-induced DNA damage and oxidative stress in HaCaT keratinocytes

Preventive effects of a water-soluble de

Preventive effects of a water-soluble derivative of chroman moiety of vitamin E on lipid hydroperoxide-induced cell injuries and DNA cleavages through repressions of oxidative stress in the cytoplasm of human keratinocytes

✍ Zhe Huang; Yuichiro Senoh; Shinya Katoh; Nobuhiko Miwa 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 553 KB

## Abstract ChrCrx (6‐hydroxy‐2, 5, 7, 8‐tetramethyl‐chroman‐2‐carboxylic acid) is a water‐soluble analog in which 4′, 8′, 12′‐trimethyltridecyl chain is deleted from an alpha‐tocopherol molecule known as a hydrophobic antioxidant. Cell viability of human skin epidermal keratinocytes HaCaT was lowe