Use of double gradient denaturing gradie
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Volker GΓΌrtler; John D. Parkin; Barrie C. Mayall
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Article
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1999
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John Wiley and Sons
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English
β 88 KB
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Gilbert's syndrome, due to reduced hepatic bilirubin glucuronidation is associated with the presence of two extra nucleotides (TA) in the promoter region of the UDP-glucuronosyltransferase 1 (UGT1A1) gene. A rapid method was developed to detect this genetic polymorphism, using double gradient denatu