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Provocative Pattern of Rearrangements of the Genes for the γ and β Chains of the T-Cell Receptor in Human Leukemias

✍ Scribed by Rakesh Goorha, Nancy Bunin, Joseph Mirro, Sharon B. Murphy, Anne H. Cross, Frederick G. Behm, Thomas Quertermous, Jon Seidman and Geoffrey R. Kitchingman


Book ID
123634657
Publisher
National Academy of Sciences
Year
1987
Tongue
English
Weight
907 KB
Volume
84
Category
Article
ISSN
0027-8424

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Rearrangement of human T cell receptor β
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## Abstract We studied rearrangement of human T cell receptor genes (TCR) of Cβ, Cγ, Vγ and Jγ in 34 cases of adult T cell leukemia/lymphoma (ATLL), consisting of 29 cases with monoclonally integrated HTLV‐I proviral DNA (ATLL‐W) and five without monoclonal integration (ATLL‐O), in comparison with