Protoporphyrin IX Fluorescence Induced in Basal Cell Carcinoma by Oral δ-Aminolevulinic Acid
✍ Scribed by Whitney D. Tope; E. Victor Ross; Nikiforos Kollias; Alex Martin; Robert Gillies; R. Rox Anderson
- Book ID
- 111412434
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 792 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0031-8655
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📜 SIMILAR VOLUMES
Laser-induced fluorescence (LIF) investigations have been performed in connection with photodynamic therapy (PDT) of basal cell carcinomas and adjacent normal skin following topical application of 5-aminolaevulinic acid (ALA) in order to study the kinetics of the protoporphyrin IX (PpIX) build-up. F
Background and Objective: 5-Aminolevulinic acid-induced protoporphyrin IX is a promising photosensitizer that could enhance the spectroscopic contrast between normal and diseased oral tissues. Knowledge of the pharmacokinetics and effects on tissue type are important for diagnostic and therapeutic p
## Abstract ## BACKGROUND The aim of the current clinical study was to evaluate the in vivo fluorescence detection of ovarian carcinoma metastases in a second‐look laparoscopic procedure after intraperitoneally applied 5‐aminolevulinic acid (ALA). ## METHODS Five hours before laparoscopic surger