Protons, pumps, and potentials: Control of cytochrome oxidase
β Scribed by Peter Nicholls; Peter Butko
- Publisher
- Springer US
- Year
- 1993
- Tongue
- English
- Weight
- 667 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0145-479X
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Cytochrome c oxidase is a redox-driven proton pump, which couples the reduction of oxygen to water to the translocation of protons across the membrane. The recently solved x-ray structures of cytochrome c oxidase permit molecular dynamics simulations of the underlying transport processes. To eventua
## ABSTRACT Proton pumping hemeβcopper oxidases represent the terminal, energyβtransfer enzymes of respiratory chains in prokaryotes and eukaryotes. The Cu~B~βheme a~3~ (or heme o) binuclear center, associated with the largest subunit I of cytochrome c and quinol oxidases, is directly involved in t