Proton NMR studies on thyrotropin releasing factor
β Scribed by Serge Fermandjian; Philippe Pradelles; Pierre Fromageot; Jean-Jacques Dunand
- Book ID
- 115903164
- Publisher
- Elsevier Science
- Year
- 1972
- Tongue
- English
- Weight
- 413 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0014-5793
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The proton magnetic resonance spectrum of thyrotropin releasing factor (TRF) in solution in deuterium oxide and deuterated dimethylsulfoxide (DMSO-d6) has been analyzed. Two forms differing in cis-trans isomerism about the His-Pro peptide bond are observed. From the temperature dependence of chemica
## Abstract The conformation of the thyrotropinβreleasing factor (TRF) and four analogs have been studied by the CNDO/2 molecular orbital method. The N^Ξ΄^βprotonated tautomer of TRF is predicted to be the more stable of the two tautomeric forms; however, it is postulated that the N^Ξ΅^βtautomer poss