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Proton MR spectroscopic imaging of the medulla and cervical spinal cord

✍ Scribed by Richard A.E. Edden; David Bonekamp; Mari A. Smith; Prachi Dubey; Peter B. Barker

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
294 KB
Volume
26
Category
Article
ISSN
1053-1807

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✦ Synopsis

Abstract

Purpose

To demonstrate the feasibility of quantitative, one‐dimensional proton MR spectroscopic imaging (1D‐MRSI) of the upper cervical spine and medulla at 3.0 Tesla.

Materials and Methods

A method was developed for 1D‐point‐resolved spectroscopy sequence (PRESS)‐MRSI, exciting signal in five voxels extending from the pontomedullary junction to the level of the C3 vertebra, and performed in 10 healthy volunteers to generate control data.

Results

High‐resolution 1D‐MRSI data were obtained from all 10 subjects. Upper cervical spine concentrations of choline, creatine, and N‐acetyl aspartate were estimated to be 2.8 ± 0.5, 8.8 ± 1.8, and 10.9 ± 2.7 mM, respectively, while in the medulla they were 2.6 ± 0.5, 9.1 ± 1.7, and 10.8 ± 0.9 mM.

Conclusion

Quantitative 1D‐MRSI of the upper cervical spine has been shown to be feasible at 3.0 Tesla. J. Magn. Reson. Imaging 2007;26:1101–1105. © 2007 Wiley‐Liss, Inc.

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