✦ LIBER ✦

Proton magnetic resonance studies on dermorphin and its peptide fragments

✍ Scribed by A. Pastore; P. A. Temussi; T. Tancredi; S. Salvadori; R. Tomatis

Publisher: Wiley (John Wiley & Sons)
Year: 1984
Tongue: English
Weight: 516 KB
Volume: 23
Category: Article
ISSN: 0006-3525
DOI: 10.1002/bip.360231116

No coin nor oath required. For personal study only.

✦ Synopsis

Dermorphin (Tyr-DAla-Phe-Gly-Tyr-Prder-NH2), a potent natural peptide opioid, its synthetic L-Ala* analog, and all the N fragments from the tripeptide (Tyr--DAla-Phe-NH,)

to the parent hexapeptide amide were characterized for the first time by means of proton nmr spectroscopy at 11.74 T. Assignments of most protons of dermorphin were facilitated by the study of the N-terminal fragments. Comparison of spectroscopic parameters with relative pharmacological activity is proposed as a possible means of studying flexible agonists in solution.

📜 SIMILAR VOLUMES

Proton Magnetic Resonance Studies on Pol

Proton Magnetic Resonance Studies on Polysaccharide Derivatives

✍ Dr. H. Friebolin; Dr. G. Keilich; Dipl.-Chem. E. Siefert 📂 Article 📅 1969 🏛 John Wiley and Sons 🌐 English ⚖ 224 KB

ChemInform Abstract: Proton Nuclear Magn

ChemInform Abstract: Proton Nuclear Magnetic Resonance Studies of the Structure of Neuropeptide Y and Its Analogues

✍ S. D. SAMARASINGHE; A. BALASUBRAMANIAM; M. E. JOHNSON 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 25 KB 👁 2 views

Studies on the conformations and interac

Studies on the conformations and interactions of elastin. Proton magnetic resonance of the repeating tetramer

✍ D. W. Urry; T. Ohnishi 📂 Article 📅 1974 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 1013 KB

Proton magnetic resonance studies of sub

Proton magnetic resonance studies of substituted 3,5-dimethylbenzenes: Influence of substituents on the methyl proton chemical shifts

✍ Fadhil S. Kamounah; Ikbal. S. Al-Sheibani; Nazar L. Shibaldain; Salman R. Salman 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 294 KB

Proton NMR data for a number of l-.IZ-4-Y-3,5-dimethylbenzenc?s and l-X-2-Y-4-Z-3,5-dimethylbenzenc?s are presented. The proton chemical shifts of the methyl groups at positions 3 and 5 are mainly affected by the ring current effect of the snbstituents. Thii conclusion was strongly supported by the

Electron paramagnetic resonance and nano

Electron paramagnetic resonance and nanosecond fluorescence depolarization studies on creatine-phosphokinase interaction with myosin and its fragments

✍ Botts, Jean ;Stone, Deborah B. ;Wang, Alice T. L. ;Mendelson, Robert A. 📂 Article 📅 1975 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 347 KB

## Abstract Recent reports in the literature have indicated a physical association of creatinephosphokinase (CPK) with the tail portion of the myosin molecule. The present paper describes further studies on the interaction of CPK with myosin and myosin fragments, using the techniques of electron pa

Proton magnetic resonance studies on con

Proton magnetic resonance studies on conformation and association of oligo-γ-benzyl-L-glutamates in solution

✍ Toyoko Imae; Shoichi Ikeda; Yuji Kobayashi; Yoshimasa Kyogoku 📂 Article 📅 1985 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 970 KB

The proton magnetic resonance spectra of enitrophenylthio-tetra-and hexa-y-benzyl-L-glutamate ethylamides have been measured at different concentrations in CDC1, and CD,,Cl. The N H and a-CH resonances of the tetrapeptide show downfield shifts with increasing concentration, accompanying disappearanc