Proton magnetic resonance studies of ribonuclease T1 Assignment of histidine-27 C2-H and C5-H proton resonances by a photooxidation reaction
✍ Scribed by R. Fülling; H. Rüterjans
- Book ID
- 115908371
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- English
- Weight
- 239 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0014-5793
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The ionization characteristics of the hydrogen-bonded His 12 AT1 proton observed to titrate between 11 to 13 ppm in the nnir spectrum of ribonuclease A in He0 solution are compared with the ionization characteristics of the four histidine CZ protons in the enzyme. Comparison of the pK,'s of the enzy
## Abstract A series of substituted hexahydropyrido [2,1‐__c__] [1,4] oxazin‐3(4__H__)‐ones has been synthesised, and the configurations of these bicyclic lactones assigned utilising chemical and spectral data. All the compounds adopt __trans__‐fused conformations and the conformation of the lacton