Proton magnetic resonance investigation of interactions between L-tryptophan and dinucleoside phosphates at low pD
✍ Scribed by N. H. Kolodny; A. C. Neville; D. L. Coleman; P. C. Zamecnik
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1977
- Tongue
- English
- Weight
- 817 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0006-3525
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✦ Synopsis
Abstract
Interactions between mononucleoside and dinucleoside phosphates containing adenine and/or cytosine and L‐tryptophan have been studied at low pD by proton magnetic resonance (pmr) spectroscopy. The results of those studies indicate that, despite extensive protonation of ring positions, and resulting electrostatic repulsion, ring stacking does occur between both like and unlike molecules. Geometries for stacked complexes are proposed and the extent of complex formation between L‐tryptophan and adenosine or cytidine in 3′ or 5′ esterified positions is discussed qualitatively.