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Proton exchange of nucleic acids: The amino protons of 5′-AMP and poly A

✍ Scribed by B. McConnell; M. Raszka; M. Mandel

Book ID
118853286
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
339 KB
Volume
47
Category
Article
ISSN
0006-291X

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Sensitive CEST agents based on nucleic acid imino proton exchange: Detection of poly(rU) and of a dendrimer-poly(rU) model for nucleic acid delivery and pharmacology
✍ Karim Snoussi; Jeff W.M. Bulte; Maurice Guéron; Peter C.M. van Zijl 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 171 KB

## Abstract It is shown that the exchange properties of the imino and hydroxyl protons of polyuridilic acid (poly(rU)) allow use of this compound as a chemical‐exchange saturation transfer (CEST) contrast agent. A proton/proton sensitivity enhancement factor of over 5000 per imino proton allowed th