Proton-Abstraction Mechanism in the Palladium-Catalyzed Intramolecular Arylation: Substituent Effects
✍ Scribed by García-Cuadrado, Domingo; de Mendoza, Paula; Braga, Ataualpa A. C.; Maseras, Feliu; Echavarren, Antonio M.
- Book ID
- 115479459
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 210 KB
- Volume
- 129
- Category
- Article
- ISSN
- 0002-7863
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Carbonylation of 4-iodotoluene in the presence of a series of 3-or 4-substituted phenols as nucleophiles using a catalytic amount of PdCl,(PPh,), and tributylamine as base to give aryl 4-methylbenzoates has been carried out. It was found that both electron-withdrawing and donating substituents on ph