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Protolimonoids and Limonoids from the Chinese Mangrove Plant Xylocarpus granatum

✍ Scribed by Jianxin Cui; Zhiwei Deng; Minjuan Xu; Peter Proksch; Qingshan Li; Wenhan Lin

Publisher: John Wiley and Sons
Year: 2009
Tongue: German
Weight: 249 KB
Volume: 92
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.200800177

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✦ Synopsis

Abstract

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The phytochemical examination of the fruits of a Chinese mangrove plant Xylocarpus granatum led to the isolation of five new protolimonoids, protoxylocarpins A–E (1–5, resp.), and two new limonoids xylocarpins J and K (6 and 7, resp.), together with xyloccensins M and Y (9 and 10, resp.). Their structures were determined on the basis of extensive spectroscopic data analysis. The cytotoxic activity of the isolated compounds against tumor cell‐lines HCT‐8, Bel‐7402, BGC‐823, and A2780 were evaluated.

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