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Protocol for gene transduction and expansion of human T lymphocytes for clinical immunogene therapy of cancer

✍ Scribed by Lamers, Cor H J; Willemsen, Ralph A; Luider, Barbara A; Debets, Reno; Bolhuis, Reinder L H


Book ID
110018911
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
427 KB
Volume
9
Category
Article
ISSN
0929-1903

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## Abstract T lymphocytes are classified into 2 subsets based on their T‐cell receptor (TCR) expression. The vast majority of T cells expresses an Ξ±Ξ² TCR heterodimer. These Ξ±Ξ² T cells recognize antigenic peptides presented by MHC class I (for CD8^+^ T cells) or MHC class II molecules (for CD4^+^ T