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Proteomics study of anthrax lethal toxin-treated murine macrophages

โœ Scribed by Jeffrey F. Kuhn; Patric Hoerth; Silvia T. Hoehn; Tobias Preckel; Kenneth B. Tomer


Book ID
102833204
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
699 KB
Volume
27
Category
Article
ISSN
0173-0835

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Proteome analysis of mouse macrophages t
โœ Harish Chandra; Pradeep K. Gupta; Kirti Sharma; Abid R. Mattoo; Satyendra K. Gar ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 562 KB

Anthrax toxin produced by Bacillus anthracis is a tripartite toxin comprising of protective antigen (PA), lethal factor (LF) and edema factor (EF). PA is the receptor-binding component, which facilitates the entry of LF or EF into the cytosol. EF is a calmodulin-dependent adenylate cyclase that caus