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Proteomics of the TRAP-induced platelet releasate

✍ Scribed by Sander R. Piersma; Henk J. Broxterman; Muhammed Kapci; Richard R. de Haas; Klaas Hoekman; Henk M.W. Verheul; Connie R. Jiménez

Book ID
104027402
Publisher
Elsevier
Year
2009
Tongue
English
Weight
765 KB
Volume
72
Category
Article
ISSN
1874-3919

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Platelets of healthy human subjects were incubated with 5-hydroxytryptamine (5-HT) followed by a second incubation with either beta-endorphin (beta-end) or the combination of beta-end and naloxone. beta-End (300 pg/ml) reduced the levels of 5-HT to 50% of initial values within 15-40 min. After 40-80