Hereditary spherocytosis (HS) is due to different membrane protein defects (i.e., deficiency of spectrin and ankyrin, band 3, or band 4.2). In order to gain new insight into the relationships between band 3 function and proteins associated with the cytoskeleton, we studied erythrocyte anion transpor
β¦ LIBER β¦
Proteomic identification of erythrocyte membrane protein deficiency in hereditary spherocytosis
β Scribed by Selen Peker; Nejat Akar; Duygu Ozel Demiralp
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 463 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0301-4851
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## Abstract How the metabolic defect of pyruvate kinase deficiency (PK(β)) accelerates red blood cell (RBC) destruction is not established, but may be related to RBC membrane abnormalities associated with altered cellular metabolism. Furthermore, it has been shown that PK(β) reticulocytes are espec