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Proteomic analysis of ERK1/2-mediated human sickle red blood cell membrane protein phosphorylation

โœ Scribed by Erik J Soderblom, J Will Thompson, Evan A Schwartz, Edward Chiou, Laura G Dubois, M Arthur Moseley, Rahima Zennadi

Book ID
119906265
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
849 KB
Volume
10
Category
Article
ISSN
1542-6416

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โœ Swati S. Ghatpande; Pankaj K. Choudhary; Charles T. Quinn; Steven R. Goodman ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier ๐ŸŒ English โš– 519 KB

Hydroxyurea (HU) is an effective drug for the treatment of sickle cell disease (SCD). The main clinical benefit of HU is thought to derive from its capacity to increase fetal hemoglobin (HbF) production. However, other effects leading to clinical benefit, such as improved blood rheology, have been s