Proteomic analysis of colonic myofibroblasts and effect on colon cancer cell proliferation
β Scribed by Andy L. Chen; Kizhake V. Soman; Piotr G. Rychahou; Bruce A. Luxon; B. Mark Evers
- Book ID
- 113920071
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 218 KB
- Volume
- 138
- Category
- Article
- ISSN
- 0039-6060
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Butyrate, a 4βcarbon fatty acid, has been shown to cause growth arrest and apoptosis of cancer cells __in vitro__ and __in vivo__. The signaling pathways leading to changes in cell growth are unclear. We used a functional proteomics approach to delineate the pathways and mediators invol
Epithelial-mesenchymal interactions play a pivotal role in colon cancer invasion and metastasis. We aimed at elucidating the impact of long-term cultivation on the phenotypic and functional characteristics of primary fibroblasts and their interaction with the human colon adenocarcinoma cell line LoV