Proteome Research: Concepts, Technology and Application

✍ Scribed by Professor Marc R. Wilkins Ph.D, Professor Ron D. Appel Ph.D (auth.), Professor Marc R. Wilkins Ph.D, Professor Ron D. Appel Ph.D, Professor Keith L. Williams Ph.D, Professor Denis F. Hochstrasser M.D (eds.)

• Publisher: Springer-Verlag Berlin Heidelberg
• Year: 2007
• Tongue: English
• Leaves: 251
• Series: Principles and Practice
• Edition: 2
• Category: Library

✦ Synopsis

Proteomics is a multifaceted, interdisciplinary field which studies the complexity and dynamics of proteins in biological systems. It combines powerful separation and analytical technology with advanced informatics to understand the function of proteins in the cell and in the body. This book provides a clear conceptual description of each facet of proteomics, describes recent advances in technology and thinking in each area, and provides details of how these have been applied to a variety of biological problems. It is written by expert practitioners in the field, from industry, research institutions, and the clinic. It provides junior and experienced researchers with an invaluable proteomic reference, and gives fascinating glimpses of the future of this dynamic field.

✦ Table of Contents

Front Matter....Pages i-xxii
Ten Years of the Proteome....Pages 1-13
Sample Preparation and Prefractionation Techniques for Electrophoresis-Based Proteomics....Pages 15-40
Protein Identification in Proteomics....Pages 41-67
Quantitation in Proteomics....Pages 69-93
One Gene, Many Proteins....Pages 95-121
Proteome Imaging....Pages 123-144
Data Integration in Proteomics....Pages 145-168
Protein–Protein Interactions....Pages 169-192
Biomedical Applications of Proteomics....Pages 193-221
Proteomics: Where to Next?....Pages 223-230
Back Matter....Pages 231-239

✦ Subjects

Proteomics; Bioinformatics; Cell Biology; Biochemistry, general; Biological Techniques