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Proteolytic stability of recombinant human serum albumin secreted in the yeastSaccharomyces cerevisiae

โœ Scribed by H. A. Kang; E.-S. Choi; W.-K. Hong; J.-Y. Kim; S.-M. Ko; J.-H. Sohn; S. K. Rhee


Publisher
Springer
Year
2000
Tongue
English
Weight
353 KB
Volume
53
Category
Article
ISSN
1432-0614

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Expression of recombinant human albumin (rHA) in Saccharomyces cerevisiae resulted in secretion of both mature albumin and a 45 kDa degradation product, comprising an N-terminal fragment of rHA with heterogeneous C-termini between residues 403 and 409 (Geisow et al., 1991). Site-directed mutagenesis