๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Proteolytic processing and degradation of human presenilin-1 expressed in yeast

โœ Scribed by Schaochuen Song; Masayuki Ohba; Yuko Saito; Toshiyuki Honda; Akihiko Takashima; Hiroshi Takahashi

Book ID
117470517
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
153 KB
Volume
282
Category
Article
ISSN
0304-3940

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Analysis of presenilin 1 and presenilin
Analysis of presenilin 1 and presenilin 2 expression and processing by newly developed monoclonal antibodies
โœ Anke Diehlmann; Nobuo Ida; Sascha Weggen; Jรผrgen Grรผnberg; Christian Haass; Coli ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 707 KB

Because distinct mutations in presenilin 1 and presenilin 2 are a major cause of early-onset familial Alzheimer's disease, we generated four monoclonal antibodies for the identification, localization, and investigation of presenilins in various cell lines and tissues from patients and controls. We s

Human presenilin-1, but not familial Alz
Human presenilin-1, but not familial Alzheimerโ€™s disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing
โœ Ralf Baumeister; Uwe Leimer; Inge Zweckbronner; Constanze Jakubek; Jรผrgen Grรผn ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Blackwell Publishing ๐ŸŒ English โš– 506 KB

The majority of cases with familial Alzheimerโ€™s disease (FAD) are linked to mutations of the presenilin (PS) genes. These genes show considerable sequence similarity to the __selโ€12__ gene of __Caenorhabditis elegans__, which has been postulated to function in the facilitated signalling by __linโ€12_