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Proteolysis of oxidised proteins and cellular senescence

โœ Scribed by K Merker; T Grune

Book ID
114253450
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
136 KB
Volume
35
Category
Article
ISSN
0531-5565

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## Abstract The model organism __Saccharomyces cerevisiae__ is providing new insights into the molecular and cellular changes that are related to aging. The yeast protein Sir2p (Silent Information Regulator 2) is a histone deacetylase involved in transcriptional silencing and the control of genomic