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Proteoglycans in cultures of skin fibroblasts in recessive dystrophic epidermolysis bullosa

โœ Scribed by Gregory, John D.; Moy, Janet A.; Damle, Shridhar P.


Book ID
122801057
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
858 KB
Volume
5
Category
Article
ISSN
0923-1811

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Collagenase and stromelysin expression in recessive dystrophic epidermolysis bullosa (RDEB) was studied at both the protein and the gene expression levels in fibroblast cultures. The amount of enzyme protein in the culture medium, as determined using a specific enzyme assay, showed a 9.7-fold increa