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Proteins that bind to the RERMS region of β amyloid precursor protein

✍ Scribed by Monika Pawlik; Deborah A.C. Otero; Minkyu Park; Wolfgang H. Fischer; Efrat Levy; Tsunao Saitoh


Book ID
116294497
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
185 KB
Volume
355
Category
Article
ISSN
0006-291X

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A novel mutation, a C to T transition at base pair 2124 in exon 17 of the amyloid beta-protein precursor (APP) gene, has been identified by direct sequencing of amplified DNA from two Alzheimer's disease (AD) patients. A simple oligonucleotide-hybridization procedure was developed to allow populatio