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Proteinase activated receptor (PAR) involvement in mediating arthritis pain and inflammation

✍ Scribed by F. A. Russell; J. J. McDougall

Book ID
105753301
Publisher
SP Birkhäuser Verlag Basel
Year
2009
Tongue
English
Weight
199 KB
Volume
58
Category
Article
ISSN
1420-908X

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✍ Jason J. McDougall; Chunfen Zhang; Laurie Cellars; Eva Joubert; Chantelle M. Dix 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 254 KB 👁 2 views

## Abstract ## Objective To investigate the role of proteinase‐activated receptor 4 (PAR‐4) in mediating joint inflammation and pain in mice. ## Methods Knee joint blood flow, edema, and pain sensitivity (as induced by thermal and mechanical stimuli) were assessed in C57BL/6 mice following intra