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Protein tyrosine phosphatase 1B negatively regulates leptin signaling in a hypothalamic cell line

โœ Scribed by Wiweka Kaszubska; H.Douglas Falls; Verlyn G Schaefer; Deanna Haasch; Leigh Frost; Paul Hessler; Paul E Kroeger; David W White; Michael R Jirousek; James M Trevillyan


Book ID
117463125
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
348 KB
Volume
195
Category
Article
ISSN
0303-7207

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CD5, a membrane-associated glycoprotein, has been shown to negatively regulate antigen receptor-mediated growth responses in peritoneal B lymphocytes, thymocytes and mature T cells. The CD5-expressing peritoneal B cells (B-1) that are normally unresponsive to B cell receptor (BCR)-mediated growth si