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Protein Tyrosine Kinase 6 Expression is Regulated by p53-Dependent and Independent Mechanisms in Response to DNA-Damage

โœ Scribed by Jessica Gierut; Ansu O. Perekatt; Angela L. Tyner


Book ID
119432433
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
40 KB
Volume
140
Category
Article
ISSN
0016-5085

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Exposure of mammalian cells to genotoxic agents evokes a complex cellular response. An ordered series of molecular events is necessary to sense DNA damage, transduce the signal, and ultimately delay the cell cycle or trigger apoptosis. Recently, we have shown that BTG2/TIS21 gene expression was indu